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This article provides a comprehensive guide to writing data to Excel files (.xlsx) in C# and ASP.NET environments. It focuses on the usage of Microsoft.Office.Interop.Excel library, covering the complete workflow including workbook creation, header setup, data population, cell formatting, and file saving. Alternative solutions using third-party libraries like ClosedXML are also compared, with practical code examples and best practice recommendations. The article addresses common issues such as data dimension matching and file path handling to help developers efficiently implement Excel data export functionality.