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This article provides an in-depth analysis of various methods for encoding binary data in JSON format, with focus on comparing space efficiency and processing performance of Base64, Base85, Base91, and other encoding schemes. Through practical code examples, it demonstrates implementation details of different encoding approaches and discusses best practices in real-world application scenarios like CDMI cloud storage API. The article also explores multipart/form-data as an alternative solution and provides practical recommendations for encoding selection based on current technical standards.