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This article examines the limitations of using wildcards in the Windows hosts file and provides a detailed guide to implementing wildcard domain resolution through Acrylic DNS Proxy. It analyzes the technical reasons why standard hosts files do not support wildcards, demonstrates the complete installation and configuration process for Acrylic, including custom hosts file editing, DNS service restart, and network settings adjustment. Combined with Apache virtual host configuration, it shows how to achieve automated domain resolution for multi-site local development, offering a comprehensive solution for developer environments.